Evidence of Work
Our assignment was to study protein synthesis, specifically through a disease. My team picked Alzheimer's to study. We split up research on the disease and on the steps of protein synthesis for Alzheimer's. The picture to the right is our final poster and the document below is our research document. Content
Protein Synthesis:the process by which amino acids are linearly arranged into proteins through the involvement of ribosomal RNA, transfer RNA, messenger RNA, and various enzymes. Codon-a sequence of three nucleotides that together form a unit of genetic code in a DNA or RNA molecule. Anti-Codon-a sequence of three nucleotides forming a unit of genetic code in a transfer RNA molecule, corresponding to a complementary codon in messenger RNA. Polymerase- an enzyme that brings about the formation of a particular polymer, especially DNA or RNA. Polypeptide Chain-Each polypeptide chain consists of smaller sub-units or amino acids that are linked together. Proteins- Primary-the characteristic sequence of amino acids forming a protein or polypeptide chain, considered as the most basic element of its structure. Secondary-the local three-dimensional structure of sheets, helices, or other forms adopted by a polynucleotide or polypeptide chain, due to electrostatic attraction between neighboring residues. Tertiary-the overall three-dimensional structure resulting from folding and covalent cross-linking of a protein or polynucleotide molecule. Quaternary-Protein quaternary structure is the number and arrangement of multiple folded protein subunits in a multi-subunit complex. Transcription-Transcription is the process of creating a complementary RNA copy of a sequence of DNA. Translation-In genetics, translation is the process by which mRNA is decoded and translated to produce a polypeptide sequence, otherwise known as a protein. Alpha Helix- the coiled structural arrangement of many proteins consisting of a single chain of amino acids stabilized by hydrogen bonds Beta Sheets-beta strands connected laterally by at least two or three backbone hydrogen bonds, forming a generally twisted, pleated sheet. Amino Acids-Amino acids are organic compounds containing amine and carboxyl functional groups, along with a side chain specific to each amino acid. DNA-a self-replicating material present in nearly all living organisms as the main constituent of chromosomes. It is the carrier of genetic information RNA- a nucleic acid present in all living cells. Its principal role is to act as a messenger carrying instructions from DNA for controlling the synthesis of proteins, although in some viruses RNA rather than DNA carries the genetic information. mRNA- is a large family of RNA molecules that convey genetic information from DNA to the ribosome, tRNA- is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. Beta Amyloid-an amyloid that is derived from a larger precursor protein and is the primary component of plaques characteristic of Alzheimer's disease |
Reflection
This wasn't my favorite project at all it was super confusing to me and a lot of it flew right over my head. Our group did a lot of really good work but our communication wasn't great. We kind of just divided up the work and then didn't really talk much about the project. One of the days I did absolutely no work whatsoever because I wasn't in a good head space at all and was focusing on calming down. I need to be able to focus all my energy into my work and not worry about my emotions as much. I could have been a bigger role and done more work in this project and that's what I'll do. Overall, I think my group and I did a good job but I would not want to do this project again if I had the chance. |